The most advanced GLP-1 weight loss medication available, now offered right here in Houston with full clinical supervision and personalized dosing. Tirzepatide works on two pathways semaglutide does not.
Tirzepatide is a dual-action weight loss medication. Where semaglutide targets one hormone pathway (GLP-1), tirzepatide targets two, GLP-1 and GIP, which regulate hunger, blood sugar, and fat storage. Activating both produces stronger appetite suppression, and in clinical trials patients lost an average of 20 to 22% of their body weight over 72 weeks (vs. 15% on semaglutide).
Tirzepatide is the active ingredient in Mounjaro and Zepbound. At PUUR we use compounded tirzepatide from a licensed compounding pharmacy, same active ingredient at a more accessible price than the brand names.
Average body weight lost in clinical trials over 72 weeks
Targets both GLP-1 and GIP pathways simultaneously
Self-administered injection with provider supervision throughout
Quick comparison to help you understand the key differences before your consultation.
TSH and HbA1c required before starting. If you have had both within the last 3 months, bring those results and the fee is waived.
Schedule a consultation with your provider. We review your health history, current medications, and weight loss goals to confirm tirzepatide is the right fit.
TSH and HbA1c are required before starting to confirm tirzepatide is safe and appropriate for you. Same-day labs available at our partner lab.
Once labs are reviewed, your prescription is written at 2.5 mg. Your provider walks you through your first injection.
Most patients find their effective dose at Tier 2 and stay there. Advancement to higher tiers is based on your progress, tolerance, and your provider’s clinical judgment, not a fixed timeline. The goal is the lowest effective dose.
What Houston patients ask before starting a tirzepatide program. Still curious? Call us at (346) 472-5888 and we will walk you through it.
Tirzepatide is the active ingredient in both Mounjaro and Zepbound. We use compounded tirzepatide from a licensed compounding pharmacy, which contains the same active ingredient at a significantly lower cost than the brand name versions. Compounded tirzepatide is not FDA approved but is legally dispensed through licensed compounding pharmacies.
Each dose tier requires more medication per monthly vial. The price reflects the increased amount of active ingredient. Your provider will always discuss a dose increase with you before it happens. You will never be moved to a higher tier without your knowledge and agreement.
The most common side effects are nausea, constipation, and reduced appetite, most pronounced during the first few weeks at each new dose level. Starting at 2.5 mg and increasing gradually is specifically designed to minimize these effects. Your provider is available throughout your program to help you manage anything that comes up.
Semaglutide activates one hormone pathway (GLP-1). Tirzepatide activates two: GLP-1 and GIP. Because it works on two pathways simultaneously, clinical trials showed greater average weight loss with tirzepatide (20 to 22 percent) compared to semaglutide (around 15 percent). It is also a good option for patients who tried semaglutide and did not achieve their desired results.
No, and most patients do not. The majority of patients find their effective dose at Tier 2 (5 to 7.5 mg at $375/month) and stay there for the duration of their program. Advancing to Tier 3, 4, or 5 is reserved for patients who genuinely need a higher dose based on their progress and response, and requires provider authorization. The program is designed around the lowest effective dose that produces results, not the highest.
Yes. If you are currently on semaglutide and want to explore tirzepatide, book a consultation and your provider will review your current dose, your results so far, and determine an appropriate starting dose for tirzepatide. In most cases, patients transitioning from semaglutide start at Tier 2 rather than beginning at the starter dose.
Semaglutide is the first-line GLP-1 option with simpler dosing and lower monthly costs. Lipo-Stat injections can support fat metabolism and energy alongside any GLP-1 program. Your provider can help you decide which combination fits your goals.
Cherry and CareCredit financing is available for every program at PUUR. Apply online in minutes and use your approval at your first visit.
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Book your tirzepatide consultation at PUUR Health and Wellness in Houston. Your provider will review your history, answer every question, and build a program around where you are today and where you want to be.
Questions about pricing or how it compares to semaglutide? Call us at (346) 472-5888.